Mechanisms of immunity in hydatid disease: implications for vaccine development.

Implications for Vaccine Development Mechanisms of Immunity in Hydatid Disease:

Innate Immunity Plays a Key Role in Leishmania Infection: Implications for Vaccine Design

Neutrophils are part of the first line of immune response and are essential for resistance against a variety of pathogens. They professionally mediate direct killing of pathogens, recruit other phagocytes by specific chemokines, produce cytokines and interact with different immune cells to shape the adaptive response. Leishmania as an obligatory intracellular parasite has evolved to benefit thi...

Effect of Immune Responses Against Hydatid Cyst Antigens on Growth of Melanoma Tumor

Background: Hydatid cyst is the larval stage of the tape worm parasite, Echinococcus granulosus. Human is infected by ingestion of parasite ova excreted in dog feces. The anticancer activity of different antigens of hydatid cyst has been reported in the previous works. In this research, the role of immune system in induction of this anticancer activity has been investigated.Materials and Method...

Experimental vaccination of sheep against hydatid cyst using EG95 recombinant vaccine

Vaccination of livestock with effective vaccine could be one of the control methods for hydatid cyst. In this study a new recombinant vaccine (Eg95) from New Zealand was prepared and used. Thirty health sheep from the same race and identical age and sex were selected. There was no history of any past vaccination or disease in selected animals. Animals were randomly categorized to four groups. O...

Isolation, Characterization and Standardization of New Infectious Bursal Disease Virus for Development of a Live Vaccine

Background and Aims: Infectious bursal disease (IBD) is an acute contagious viral disease of birds worldwide. The causative virus induces a persistent immune suppression following destroy B lymphocytes precursors in bursal lymphoid follicles. Vaccination is the main strategy for prevention of the disease in commercial poultry industry. Materials and Methods: To produce a live vaccine against th...